![]() ![]() Guillain-Barre syndrome may be triggered by: It's also slightly more common in males than females. Guillain-Barre syndrome can affect all age groups, but your risk increases as you age. The damage prevents nerves from transmitting signals to your brain, causing weakness, numbness or paralysis. In AIDP, the nerves' protective covering (myelin sheath) is damaged. ![]() In Guillain-Barre syndrome, your immune system - which usually attacks only invading organisms - begins attacking the nerves. It's also a rare reaction in those who receive the Johnson & Johnson or AstraZeneca COVID-19 vaccine. Guillain-Barre syndrome may occur after infection with the COVID-19 virus. There have been cases reported following infection with the Zika virus. Rarely, recent surgery or vaccination can trigger Guillain-Barre syndrome. The disorder usually appears days or weeks after a respiratory or digestive tract infection. The exact cause of Guillain-Barre syndrome isn't known. The sooner appropriate treatment is started, the better the chance of a good outcome. Guillain-Barre syndrome is a serious condition that requires immediate hospitalization because it can worsen rapidly.
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